Cats can be very difficult when it comes to grooming. If you’re lucky enough to have a cat who actually likes to be brushed, then great, but if your cat squirms, hisses, and runs away every time you take out the brush, then maybe this tip will help. Try giving your cat a toy that will occupy him while you brush. If he likes catnip, that may even be more enticing for him. He will concentrate on biting the cat toy with catnip rather than you. He may also stay put while you groom him. My older cat loves to be brushed and even cries for more after I’m finished. My younger cat will do anything to get away and she’s a squirmy one. She will twist herself out of anything!  Try the toy and who knows, this may solve your problem.