Pets with one blue eye and one brown eye is called complete heterochromia. It’s the way the pigment melanin is distributed in an animals’ skin and hair. A dog or cat that has complete heterochromia has a white area of skin and hair around it’s eye where there’s little or no melanin. The result is one blue eye.  Plenty of melanin is concentrated in the other eye which is a different color.  The reason for this is unclear. Complete heterochromia is seen quite often in cats, horses and other animals. Partial heterochromia where the iris of the eye is two different colors is much more unusual.  Why this occurs is not clearly understood. It is believed to be inherited in most cases.

Information obtained from Animal Instincts.

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